Presentation of the Centre
CRO - Institute for Research, Hospitalization and Health Care (IRCCS) opened in 1984 and accredited by the Italian Ministry of Health in 1990 - is a public, no-profit institute that operates under the authority of the Italian Ministry of Health for the clinical & experimental research functions and under the governance of the Friuli Venezia Giulia Region for patients’ care.
Main research activity
The current research activity at CRO is based on five lines which are consistent with the Institute’s objectives, i.e. translational research in oncology and precision medicine, mainly preclinical. The lines are:
- Tumor genetics and biology
- Tumor epidemiology, prevention and health big data
- Lympho-hematologic neoplasias
- Solid tumors
Clinical research is based on mono- and multidisciplinary therapeutic protocols (conservative surgery in breast cancer; combined chemotherapy and radiotherapy in locally advanced lung cancer; interdisciplinary treatment of intestinal and ovarian tumors and soft tissue sarcomas. Experimental research focuses on: gene alterations; neoplastic transformation and progression; mechanisms of cell adhesion and migration; role of growth factors and growth factor receptors in lympho-hematological neoplasias; mechanisms of drug sensitivity and resistance; mechanisms of action of non-genetic cancer risk factors.
Core Facilities
- Pharmacogenomics
- Proteomics
- Flow cytometry
- Biobanking
- Centralized clinical trials office
- Genomics
- Animal Facility
- In vitro and in vivo imaging
Education
Collaborations with the Universities of Trieste, Udine and others allow the presence at CRO of residents in medical oncology and other relevant disciplines and PhD students. Students can find hospitality in the nearby Campus that also hosts educational facilities.